Courtney Lowes and Manu Tuilagi are returning to England starting in the XV, to visit Wales for Saturday’s match against Wales.
The combination in the midfield of Marcus Smith, Manu Tuilaga and Henry Slade makes English fans lick their lips.
Head coach Eddie Jones: “Marcus has an easy arm, fast legs, the ability to beat people one on one in space. Slady has an educated left foot and the ability to take breaks, as well as the power of Manu. Manu gives us another way to wear on the back.
“If he’s not there, we don’t have that big back to play. It’s convenient to have such a big back to create space. “
In the front row hooker Luke Cowen-Dicky starts in place of Jamie George, while props Kyle Sinclair pushes Will Stewart to the bench to come out in his 50th match in England.
Lowes has not played since mid-January due to a concussion, but has been found both fit to start and to regain the captaincy he had against South Africa in the autumn, and winger Tom Curry has resigned.
Eddie Jones said: “Courtney was going to be captain when Owen was unavailable. He has good skills around the player. When he speaks, people listen, and he sets an example. ”
During Curry’s debut as international captain, Jones noted that he is very pleased with his first two games as captain.
Aside from the captaincy, Jones said, “Courtney is a great ball carrier.”

When teammate from Northampton Dan Biggar leads Wales, this is the first time in history that the captains in England’s match against Wales both come from the same club.
Youngs must break Jason Leonard’s record of 114 appearances for England if he enters the field at Twickenham.
Eddie Jones said, “We have Ben Youngs to finish the game. These games always tend to go to the wire. Imagine that in this situation the guy comes out with 115 matches.
Harry Randall starts the game while England is aiming for a flying start.
“Harry’s getting better every week,” Jones said.
“We want to give some pace to the game earlier. There will be opportunities at the beginning of the game. ”

England lost their opening game against Scotland before winning in Italy with bonus points, which means they really need a win against Wales to keep their hopes of the title.
Last year’s Welsh winners – who recalled winger Josh Adams and eighth-seeded Toulouse Faletov – also won one victory and lost in one of their matches.
The England national team will meet Wales: steward; Malins, Slade, Tuilagi, Knowell; Smith, Randall; Genge, Cowen-Dickie, Sinclair, Eveles, Itohe, Lowes (Hoof), Curry, Dumbrandt.
Replacements: George, Marler, Stewart, Izikwe, Simmonds, Youngs, Ford, Daly.
The Welsh national team will meet England: Liam Williams; Alex Cuthbert; Owen Watkin; Nick Tompkins; Josh Adams; Dan Biggar (Captain); Thomas Williams; Win Jones; Ryan Elias; Tomasz Franciszek; Will Rowlands; Adam Beard; Ross Mariarty; Tain Basham; Taulupe Falet.
Replacements: Lake, J. Thomas, Brown, S. Davis, Morgan, Hardy, Enscombe, J. Davis.